The ghetto of Siena was founded by Cosimo I de’ Medici in 1571. It was built in an urban elongated space behind Piazza del Campo, between via del Salicotto and via San Martino, and was traversed by parallel streets such as via delle Scotte and the laneways of Luparello, Realto, Fortuna, Manna, Coda, and Vannello.
This was where daily life of Jewish people took place: in via delle Scotte, at number 14, the synagogue is still present; the schools and the different confraternities were based in vicolo del Luparello. The fountain of the ghetto was in via degli Archi, adorned since the sixteenth century with a statue of Moses, perhaps by Jacopo della Quercia (removed in 1875 and now in the City Museum). The ghetto was a real city within the city, and very culturally vibrant, in which up to five rabbinical schools were established.
It remained open until 1859. Some areas are still preserved and recognisable; much of the area, however, was restored as part of a redevelopment in 1935.